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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2307696Generated: October 31, 2026

O-(Tetrahydropyran-2-yl)hydroxylamine → 5-{[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl(3-{[(tetrahydro-2H-pyran-2-yloxy)imino]methyl}benzyl)amino]carbonyl}-1,2,4-benzenetricarboxylic Acid

https://huagongshe.com/reaction/2307696

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-(Tetrahydropyran-2-yl)hydroxylamineHCID 5142091—
Reactant5-({(3-formylbenzyl)[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino}carbonyl)-1,2,4-benzenetricarboxylic AcidHCID 10228835—
Product5-{[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl(3-{[(tetrahydro-2H-pyran-2-yloxy)imino]methyl}benzyl)amino]carbonyl}-1,2,4-benzenetricarboxylic AcidHCID 86586457—

Reaction Steps

The product from Example 76E and O-tetrahydro-2H-pyran-2-ylhydroxylamine were processed as described in Example 76F to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06831193B2
Source datasetuspto-grants-2004_12
ORD IDord-e06de2a7680446c093ef9d74346a892d
Source noteuspto-grants-2004_12