HRID2307699

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID122308

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine

C7H4F5NO

结构：O=Cc1cccc(CN(C(=O)c2cc(C(=O)O)c(C(=O)O)cc2C(=O)O)[C@H]2CCCc3ccccc32)c1

HCID10228835

未命名化合物

PRODUCTS

生成物

结构：O=C(O)c1cc(C(=O)O)c(C(=O)N(Cc2cccc(C=NOCc3c(F)c(F)c(F)c(F)c3F)c2)[C@H]2CCCc3ccccc32)cc1C(=O)O

HCID86586461

未命名化合物

PROCEDURE

实验过程

The product from Example 76E and O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine were processed as described in Example 76F to provide the title compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-dfa0a884a7204da7a5577a6c2b33b06e
来源数据集: uspto-grants-2004_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06831193B2
来源说明: uspto-grants-2004_12

反应 SMILES

[CH:1]([C:3]1[CH:4]=[C:5]([CH:35]=[CH:36][CH:37]=1)[CH2:6][N:7]([C@@H:25]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH2:28][CH2:27][CH2:26]1)[C:8]([C:10]1[CH:15]=[C:14]([C:16]([OH:18])=[O:17])[C:13]([C:19]([OH:21])=[O:20])=[CH:12][C:11]=1[C:22]([OH:24])=[O:23])=[O:9])=O.[F:38][C:39]1[C:47]([F:48])=[C:46]([F:49])[C:45]([F:50])=[C:44]([F:51])[C:40]=1[CH2:41][O:42][NH2:43]>>[F:38][C:39]1[C:47]([F:48])=[C:46]([F:49])[C:45]([F:50])=[C:44]([F:51])[C:40]=1[CH2:41][O:42][N:43]=[CH:1][C:3]1[CH:4]=[C:5]([CH:35]=[CH:36][CH:37]=1)[CH2:6][N:7]([C@@H:25]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH2:28][CH2:27][CH2:26]1)[C:8]([C:10]1[CH:15]=[C:14]([C:16]([OH:18])=[O:17])[C:13]([C:19]([OH:21])=[O:20])=[CH:12][C:11]=1[C:22]([OH:24])=[O:23])=[O:9]