HCID 10144017, compound → HCID 10218386, compound

HRID 2307710Notes

Reaction equation

HRID 2307710 reaction equation
BrC1C=C(C=CC=1)[CH2:5][N:6]([C@@H:24]1[C:33]2[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=2)[CH2:27][CH2:26][CH2:25]1)[C:7]([C:9]1[CH:14]=[C:13]([C:15]([OH:17])=[O:16])[C:12]([C:18]([OH:20])=[O:19])=[CH:11][C:10]=1[C:21]([OH:23])=[O:22])=[O:8].[S:37]1[CH:41]=[CH:40][CH:39]=[C:38]1[C:42]1[CH:43]=[C:44](B(O)O)[CH:45]=[CH:46][CH:47]=1>>[C@@H:24]1([N:6]([CH2:5][C:44]2[CH:45]=[CH:46][CH:47]=[C:42]([C:38]3[S:37][CH:41]=[CH:40][CH:39]=3)[CH:43]=2)[C:7]([C:9]2[CH:14]=[C:13]([C:15]([OH:17])=[O:16])[C:12]([C:18]([OH:20])=[O:19])=[CH:11][C:10]=2[C:21]([OH:23])=[O:22])=[O:8])[C:33]2[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=2)[CH2:27][CH2:26][CH2:25]1

Participants

3

Reactant 2

HCID 10144017HCID 10144017, compoundHCID 22388587HCID 22388587, compound

Product 1

HCID 10218386HCID 10218386, compound

Procedure

The product from Example 15B (165 mg, 0.3 mmol) and 3-(2-thienyl)phenylboronic acid were processed as described in Example 85 to provide the title compound.

Sources & evidence

ORD record
ord-1c2a6be10d554521950dffc5a7a7068d
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

Loading…