Acetic Anhydride → HCID 85612101, compound

HRID 2307716Notes

Reaction equation

HRID 2307716 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([C:14]([OH:16])=[O:15])[C:5]([C:11]([OH:13])=O)=[CH:6][C:7]=1[C:8]([OH:10])=[O:9].[C:17](OC(=O)C)(=[O:19])[CH3:18]>>[C:17]([O:1][C:2]1[C:7]([C:8]([OH:10])=[O:9])=[CH:6][C:5]2[C:11](=[O:13])[O:16][C:14](=[O:15])[C:4]=2[CH:3]=1)(=[O:19])[CH3:18]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 28017655-hydroxybenzene-1,2,4-tricarboxylic acid

Product 1

HCID 85612101HCID 85612101, compoundYield 38%

Procedure

4-Hydroxy-benzene-1,2,5-tricarboxylic acid (4.1 g, 18.1 mmol), prepared according to J. Am. Chem. Soc. (1949) 71, 11, was treated with acetic anhydride (50 mL) and heated at reflux for 5 hours. The mixture was allowed to cool to room temperature and then concentrated under reduced pressure. The orange-pink residue was washed with diethyl ether (3×30 mL) and dried under reduced pressure at room temperature overnight to provide the title compound (1.71 g, 38%).

Workup

  1. temperatureheated
  2. temperatureat reflux for 5 hours
  3. concentrationconcentrated under reduced pressure
  4. washThe orange-pink residue was washed with diethyl ether (3×30 mL)
  5. customdried under reduced pressure at room temperature overnight

Sources & evidence

ORD record
ord-5c303af4991e4d21b6ccb61744dd24ca
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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