HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Pyrimidin-2-yloxy)benzaldehyde → HCID 69720977, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Pyrimidin-2-yloxy)benzaldehyde | HCID 2763336 | — |
| Reactant | 1-Aminotetralin, (S)- | HCID 7058074 | — |
| Product | HCID 69720977 | HCID 69720977 | 19% |
Reaction Steps
3-(2-Pyrimidinyloxy)benzaldehyde (0.67 g, 3.35 mmol) and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine (0.49 g, 3.33 mmol) were processed as described in Example 106A. The residue was purified by flash chromatography (silica gel, 6:4 ethyl acetate:hexanes to 1:1 ethyl acetate:hexanes) to provide the title compound (190 mg, 19% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06831193B2 |
| Source dataset | uspto-grants-2004_12 |
| ORD ID | ord-2ff3f4601aa64264b909c330c02241e3 |
| Source note | uspto-grants-2004_12 |