Methanol → Methyl 3-fluoro-4-hydroxybenzoate

Beteiligte Stoffe

Reaktionsschritte

A commercial product, 3-fluoro-4-hydroxybenzoic acid hydrate (1.1 g) was dissolved in methanol (11 mL), and in an ice bath, thionyl chloride (0.77 mL) was added thereto, and heated under reflux for 2 hours. After the reaction, the reaction liquid was entirely concentrated to obtain the entitled compound (1.1 g).

Herkunft & Nachweise