Picolyl chloride hydrochloride → HCID 10775701, compound

HRID 230777Notes

Reaction equation

HRID 230777 reaction equation
[F:1][C:2]1[CH:9]=[C:8]([OH:10])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].Cl.Cl[CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=1>>[F:1][C:2]1[CH:9]=[C:8]([O:10][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)[CH:7]=[CH:6][C:3]=1[C:4]#[N:5]

Participants

3

Reactant 2

HCID 23392Picolyl chloride hydrochlorideHCID 27346752-Fluoro-4-hydroxybenzonitrile

Product 1

HCID 10775701HCID 10775701, compoundYield 72.1%

Procedure

2-Fluoro-4-hydroxybenzonitrile (1.0 g) and 2-chloromethylpyridine hydrochloride (1.2 g) were processed in the same manner as in Production Example 1-1 to obtain the entitled compound (1.2 g).

Sources & evidence

ORD record
ord-ad0cf48f93ae4cc792f082f3ea2b4ba5
Source dataset
uspto-grants-2009_07
Patent number
US07566781B2

Reaction notes

Loading…