Nitric Acid → HCID 22602613, compound

Participants

Reaction Steps

Boronophthalide (2.86 g, 21.4 mmol) is added to 18.6 mL of chilled, fuming nitric acid (at 45° C.) in portions over 4 minutes with stirring. The reaction is quenched with ice and water (40 g and 60 mL), then the resulting pale yellow solid is collected on a Büchner filter and washed with 75 mL of water. Drying the solid in vacuo over P2O5 gives 2.72 g (15.2 mmol, 71.0%) 5-Nitroboronophthalide as a pale yellow solid (m.p. 178-179° C.).

Provenance & Evidence