Triacetoxyperiodinane → HCID 86584332, compound

Participants

Reaction Steps

A mixture of 2-(4-chloro-2,6-dimethyl-phenoxy)-4-(1-hydroxymethyl-propylamino)-6-methyl-nicotinamide and Dess-Martin reagent in methylene chloride/DMSO was stirred at rt for 4 hr. The title compound was isolated after standard work-up and silica gel Biotage purification. 1H NMR(CDCl3) d 9.52(s,1H), 8.00(brs,1H), 7.06(s,22H), 5.99(s,1H), 5.8(brs,1H), 3.85(m,1H), 2.09(s,3H), 2.08(s,6H), 1.8-2.2(m,2H), 1.08(t,3H) ppm.

Provenance & Evidence