Morpholine → N-[3-methyl-2-(3-morpholin-4-ylpropyl)imidazo[1,2-a]pyridin-6-yl]-4-(pyridin-2-ylmethoxy)benzamide
Reaction equation
O[CH2:2][CH2:3][CH2:4][C:5]1[N:6]=[C:7]2[CH:12]=[CH:11][C:10]([NH:13][C:14](=[O:29])[C:15]3[CH:20]=[CH:19][C:18]([O:21][CH2:22][C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][N:24]=4)=[CH:17][CH:16]=3)=[CH:9][N:8]2[C:30]=1[CH3:31].[NH:32]1[CH2:37][CH2:36][O:35][CH2:34][CH2:33]1>>[CH3:31][C:30]1[N:8]2[CH:9]=[C:10]([NH:13][C:14](=[O:29])[C:15]3[CH:16]=[CH:17][C:18]([O:21][CH2:22][C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][N:24]=4)=[CH:19][CH:20]=3)[CH:11]=[CH:12][C:7]2=[N:6][C:5]=1[CH2:4][CH2:3][CH2:2][N:32]1[CH2:37][CH2:36][O:35][CH2:34][CH2:33]1Participants
3
Procedure
The compound (20.0 mg) obtained in Example 14 and morpholine (1 mL) were processed in the same manner as in Production Example 46-3 to obtain the entitled compound (13.0 mg).
Sources & evidence
- ORD record
- ord-b3f6d2e56acf42a4ad29e4c2a6d9f583
- Source dataset
- uspto-grants-2009_07
- Patent number
- US07566781B2
Reaction notes
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