(Diethylamino)sulfur trifluoride → HCID 11582144, compound

Participants

Reaction Steps

DAST (20 μL) was added to a chloroform solution (6 mL) of the compound (16 mg) obtained in Example 54, and stirred at room temperature for 5 hours. Aqueous saturated sodium hydrogencarbonate solution was added to the reaction liquid, and extracted with ethyl acetate. The organic layer was washed with water and saturated saline water, and dried with anhydrous sodium sulfate. The organic layer was concentrated under reduced pressure, and the residue was purified through silica gel column chromatography (chloroform/methanol=90/1) to obtain the entitled compound (10 mg) as a brown solid.

Provenance & Evidence