HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-1-hexanol → (E)-4-butoxy-3-methoxycinnamic acid 6-hydroxyhexyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-1-hexanol | HCID 74828 | — |
| Reactant | 3-(4-Butoxy-3-methoxyphenyl)prop-2-enoic acid | HCID 5933564 | — |
| Product | (E)-4-butoxy-3-methoxycinnamic acid 6-hydroxyhexyl ester | HCID 20744698 | 79.3% |
Reaction Steps
Following the procedure of Example 1 and using 1.38 g (5.50 mmol) (E)-4butoxy-3-methoxycinnamic acid, 0.84 g (5.50 mmol) 1,8-diazabicyclo[5.4.0]undec-7-ene(1,5-5) (DBU) and 0.68 g (5.0 mmol) 6-chlorohexanol gave 1.39 g (79%) (E)-4-butoxy-3-methoxycinnamic acid 6-hydroxyhexyl ester as colourless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06833421B1 |
| Source dataset | uspto-grants-2004_12 |
| ORD ID | ord-0589173670524242b5cbf1f7b5de155d |
| Source note | uspto-grants-2004_12 |