Nitric Acid → HCID 12134605, compound

HRID 2308190Notes

Reaction equation

HRID 2308190 reaction equation
[CH3:1][O:2][CH2:3][CH:4]1[CH2:9][O:8][C:7]2[CH:10]=[CH:11][C:12]([C:14]([OH:16])=[O:15])=[CH:13][C:6]=2[O:5]1.[N+:17]([O-])([OH:19])=[O:18].S(=O)(=O)(O)O.O>C(O)(=O)C>[CH3:1][O:2][CH2:3][CH:4]1[CH2:9][O:8][C:7]2[CH:10]=[C:11]([N+:17]([O-:19])=[O:18])[C:12]([C:14]([OH:16])=[O:15])=[CH:13][C:6]=2[O:5]1

Participants

6

Reactant 4

HCID 944Nitric AcidHCID 962WaterHCID 1118Sulfuric AcidHCID 12134604HCID 12134604, compound

Product 1

HCID 12134605HCID 12134605, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

The titled compound of Example 3 (0.788 g, 3.51 mmol) was dissolved in 2 ml of acetic acid, and added a mixture of nitric acid (3 ml) and sulfuric acid (3 ml), followed by stirring for 30 min. Then, to the reaction mixture was added 10 ml of water to give a solid, which was then fitered and washed with acetic acid and ether in a sequential order to prepare the titled compound (0.510 g, 54%).

Workup

  1. additionadded
  2. customto give a solid, which
  3. washwashed with acetic acid and ether in a sequential order
  4. customto prepare the titled compound (0.510 g, 54%)

Sources & evidence

ORD record
ord-33ce4d7794f74761993325aa2bea590f
Source dataset
uspto-grants-2004_12
Patent number
US06835735B2

Reaction notes

Loading…