3-Fluoro-4-methoxyphenylboronic acid → HCID 10473862, compound

Participants

Reaction Steps

Starting from 2-[3-bromo-5-(3-chloro-4-methoxyphenyl)-4-methylthien-2-yl]-1,3-dioxolane (1.0 g, 2.6 mmol, made in Example 13, Step 1) and substituting 3-fluoro-4-methoxyphenylboronic acid (0.52 g, 3.1 mmol) in place of 3-methoxyphenylboronic acid (Step 2), the title compound (0.26 g, 51%, m.p. 227-29° C.) was synthesized in essentially the same manner as described in Example 1, Steps 2-4.

Provenance & Evidence