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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 230841Generated: October 30, 2026

3-Methoxyaniline → 7-Chloro-8-methyl-4-{[3-(methyloxy)phenyl]amino}-3-quinolinecarboxamide hydrochloride

https://huagongshe.com/reaction/230841

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxyanilineHCID 10824—
Reactant4,7-Dichloro-8-methyl-3-quinolinecarboxamideHCID 57763233—
Reactant6-Iodo-4-{[3-(methyloxy)phenyl]amino}-3-quinolinecarboxamide hydrochlorideHCID 67424605—
Product7-Chloro-8-methyl-4-{[3-(methyloxy)phenyl]amino}-3-quinolinecarboxamide hydrochlorideHCID 67423816—

Reaction Steps

Intermediate 66 was prepared from Intermediate 68 using 3-methoxyaniline in a similar manner to Intermediate 14.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07566786B2
Source datasetuspto-grants-2009_07
ORD IDord-63c9240f3a254eac950e5d97c8942165
Source noteuspto-grants-2009_07