HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,6-Dibromohexane → 1-[4-[(6-Bromohexyl)oxy]butyl]benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,6-Dibromohexane | HCID 12368 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Benzenebutanol | HCID 76889 | — |
| Catalyst | Tetrabutylammonium hydrogen sulfate | HCID 94433 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-[4-[(6-Bromohexyl)oxy]butyl]benzene | HCID 11012439 | — |
Reaction Steps
At a temperature between 20 and 25° C., with stirring, a mixture of 247.5 ml (1.65 mol) of 4-phenylbutanol and 500 ml of toluene are added within 45 minutes to a mixture of 509.6 ml (3.3 mol) of 1,6-dibromohexane, 402 g of powdered (6.1 mol KOH) caustic potash, 5.6 g (0.165 mol) tetra-n-butylammonium hydrogen sulphate and 1250 ml of toluene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06835857B2 |
| Source dataset | uspto-grants-2004_12 |
| ORD ID | ord-770c18dbbf1642cc8e2ab725a7e65b23 |
| Source note | uspto-grants-2004_12 |