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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2308469Generated: November 1, 2026

5-Methylthiophene-2-carbonyl chloride → 5-Methyl-thiophene-2-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide

https://huagongshe.com/reaction/2308469

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Methylthiophene-2-carbonyl chlorideHCID 2760083—
Reactant4-Methoxy-7-morpholinobenzo[d]thiazol-2-amineHCID 11402861—
Product5-Methyl-thiophene-2-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amideHCID 8658491397%

Reaction Steps

Using 5-methyl-thiophene-2-carbonyl chloride and 2-amino-4-methoxy-7-morpholin-4-yl-benzothiazol the title compound was obtained as a yellow solid in 97% yield. MS: m/e=390 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06835732B2
Source datasetuspto-grants-2004_12
ORD IDord-7ea6d43e057d42cc92d39304b9acb66e
Source noteuspto-grants-2004_12