HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → N-(4-Ethoxy-7-piperidin-1-yl-benzothiazol-2-yl)-4-fluoro-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-fluoro-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-benzamide | HCID 10200214 | — |
| Reactant | 4-Bromo-1-ethoxy-2-nitrobenzene | HCID 22283188 | — |
| Product | N-(4-Ethoxy-7-piperidin-1-yl-benzothiazol-2-yl)-4-fluoro-benzamide | HCID 22283331 | — |
Reaction Steps
The title compound was prepared strarting from 4-bromo-1-ethoxy-2-nitro-benzene and piperidine as described for 4-fluoro-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-benzamide (Example 275) and obtained as a yellow solid in 10% overall yield, MS: m/e=400 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06835732B2 |
| Source dataset | uspto-grants-2004_12 |
| ORD ID | ord-90d42d10e15b48ada8b8602124e11044 |
| Source note | uspto-grants-2004_12 |