Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1) → Methyl 5-[2'-chloro-4'-(trifluoromethyl)phenoxy]-2-nitrobenzimidate

HRID 2308584Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2308584
F[B-](F)(F)F.[CH3:6][O+](C)C.[Cl:10][C:11]1[CH:29]=[C:28]([C:30]([F:33])([F:32])[F:31])[CH:27]=[CH:26][C:12]=1[O:13][C:14]1[CH:15]=[CH:16][C:17]([N+:23]([O-:25])=[O:24])=[C:18]([CH:22]=1)[C:19]([NH2:21])=[O:20]>C(Cl)Cl>[Cl:10][C:11]1[CH:29]=[C:28]([C:30]([F:31])([F:32])[F:33])[CH:27]=[CH:26][C:12]=1[O:13][C:14]1[CH:15]=[CH:16][C:17]([N+:23]([O-:25])=[O:24])=[C:18]([CH:22]=1)[C:19](=[NH:21])[O:20][CH3:6]

Komponenten

4

Edukt 2

HCID 2735153Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1)HCID 153350195-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzamide

Produkt 1

HCID 15592968Methyl 5-[2'-chloro-4'-(trifluoromethyl)phenoxy]-2-nitrobenzimidateAusbeute 95 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

A solution containing trimethyloxonium tetrafluoroborate (100 g; 0.68 mol) and methylene chloride (2 liters) is prepared. It is stirred and 5-[2'-chloro-4'-(trifluoromethyl)phenoxy]-2-nitrobenzamide (220 g; 0.61 mol) is then added in portions at ambient temperature. The stirring is continued for 24 hours at ambient temperature. The solution is then washed with a 10% aqueous solution of sodium carbonate (cooled beforehand) and dried over sodium sulphate. The methylene chloride is removed by evaporation to leave a yellow solid of methyl 5-[2'-chloro-4'-(trifluoromethyl)phenoxy]-2-nitrobenzimidate (217 g; yield 95%) melting at 46° C. and having the formula: ##STR20##

Aufarbeitung

  1. customis prepared
  2. washThe solution is then washed with a 10% aqueous solution of sodium carbonate (cooled beforehand)
  3. dry with materialdried over sodium sulphate
  4. customThe methylene chloride is removed by evaporation

Quellen und Nachweise

ORD-Eintrag
ord-b94d13e0351841eba307334afd0058be
Quelldatensatz
uspto-grants-1987_09
Patentnummer
US04690708

Notizen zur Reaktion

Wird geladen…