1-Methyl-4-nitro-2,3-dihydro-1H-indole → 1-methyl-2,3-dihydro-1H-indol-4-amine

Participants

Reaction Steps

A solution of Intermediate 70 (0.50 g) in ethanol (30 ml) was added to 10% palladium on carbon (0.050 g) and the mixture was stirred under an atmosphere of hydrogen for 20 min. The mixture was filtered through ‘hyflo’ filter aid and the solvent removed in vacuo to give the title compound as a brown oil (0.405 g).

Provenance & Evidence