HCID 70381481, compound → HCID 20187420, compound

HRID 2308609Notes

Reaction equation

HRID 2308609 reaction equation
[NH:1]1[CH:5]2[C:6]3[N:11]([CH2:12][CH2:13][CH:4]2[S:3][CH:2]1NC)[CH2:10][CH:9]=[CH:8][CH:7]=3.Cl.N1C2C3N(CCC2SC1N(C)S(N(C)C)(=O)=[O:32])CC=CC=3>>[NH:1]1[CH:5]2[C:6]3[N:11]([CH2:12][CH2:13][CH:4]2[S:3][C:2]1=[O:32])[CH2:10][CH:9]=[CH:8][CH:7]=3

Participants

3

Reactant 2

HCID 70381481HCID 70381481, compoundHCID 131715241HCID 131715241, compound

Product 1

HCID 20187420HCID 20187420, compound

Procedure

Following the procedures substantially as described in Example 1, Steps F and G but substituting for the quinolizin-2-one used therein, an equimolar amount of the quinolizin-2-one from Step G of this Example 13, there are produced in sequence: (2RS,10bSR)-N-(1,3,4,6,7,10b-hexahydro-2H-thiazolo[4,5-a]quinolizin-2-yl)-N-methylamine; and (2RS,10bSR)-N-(1,3,4,6,7,10b-hexahydro-2H-thiazolo[4,5-a]quinolizin-2-yl)-N,N',N'-trimethylsulfamide, hydrochloride.

Sources & evidence

ORD record
ord-b48b983f47d644a8bd984423ad099579
Source dataset
uspto-grants-1987_09
Patent number
US04690928

Reaction notes

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