1-Piperazinecarboxaldehyde → HCID 178521670, compound

HRID 2308663Notes

Reaction equation

HRID 2308663 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:13]2[CH2:18][CH2:17][S:16](=[O:19])[CH2:15][CH2:14]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([SH:12])[C:6]=2[N:7]=1.[CH:20]([N:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1)=[O:21]>>[CH:20]([N:22]1[CH2:27][CH2:26][N:25]([C:2]2[N:3]=[C:4]([N:13]3[CH2:18][CH2:17][S:16](=[O:19])[CH2:15][CH2:14]3)[C:5]3[N:11]=[CH:10][N:9]=[C:8]([SH:12])[C:6]=3[N:7]=2)[CH2:24][CH2:23]1)=[O:21]

Participants

3

Reactant 2

HCID 821911-PiperazinecarboxaldehydeHCID 178527115HCID 178527115, compound

Product 1

HCID 178521670HCID 178521670, compound

Procedure

This compound was prepared analogous to Example 93 from 2-chloro-8-mercapto-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p.: >280° C., decomp.) and N-formylpiperazine.

Sources & evidence

ORD record
ord-5e0b8d7a02b543348ae26bd6a9705efb
Source dataset
uspto-grants-1987_09
Patent number
US04690923

Reaction notes

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