反应详情

14.8 g (0.1 mol) of 4'-methylpropiophenone are introduced into 100 ml of chloroform, in the presence of a small amount of finely ground aluminium chloride, and a solution of 15.9 g (0.1 mol; 5 ml) of bromine, in 20 ml of chloroform is added dropwise whilst cooling with an ice bath. The mixture is left to react overnight at ambient temperature. It is then filtered, the solvent is evaporated off from the filtrate and the crystalline residue is washed with diethyl ether. 21.5 g of crystals are collected.

1. temperaturewhilst cooling with an ice bath
2. waitThe mixture is left
3. customto react overnight at ambient temperature
4. filtrationIt is then filtered
5. customthe solvent is evaporated off from the filtrate
6. washthe crystalline residue is washed with diethyl ether
7. custom21.5 g of crystals are collected