Sulfuric acid magnesium salt (1:1) → HCID 70443455, compound

HRID 2308812Notes

Reaction equation

HRID 2308812 reaction equation
[Br:1][C:2]1[C:13]2=[C:14]3[N:9]([CH:10]([CH3:15])[CH2:11][CH2:12]2)[CH:8]=[C:7]([C:16]([O-:18])=[O:17])[C:6](=[O:19])[C:5]3=[CH:4][C:3]=1[F:20].[Na+].S([O-])([O-])(=O)=O.[Mg+2:27]>O>[OH2:17].[Br:1][C:2]1[C:13]2=[C:14]3[N:9]([CH:10]([CH3:15])[CH2:11][CH2:12]2)[CH:8]=[C:7]([C:16]([O-:18])=[O:17])[C:6](=[O:19])[C:5]3=[CH:4][C:3]=1[F:20].[Mg+2:27].[Br:1][C:2]1[C:13]2=[C:14]3[N:9]([CH:10]([CH3:15])[CH2:11][CH2:12]2)[CH:8]=[C:7]([C:16]([O-:18])=[O:17])[C:6](=[O:19])[C:5]3=[CH:4][C:3]=1[F:20]

Participants

4

Reactant 2

HCID 24083Sulfuric acid magnesium salt (1:1)HCID 23707684HCID 23707684, compound

Product 1

HCID 70443455HCID 70443455, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A solution of 1.0 g of sodium 8-bromo-6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylate in 30 ml of warm water was stirred with 1 g magnesium sulfate in 20 ml of water and warmed on a steam bath for 15 minutes. Cooling and filtration provided magnesium 8-bromo-6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylate hydrate, m.p. >300° C.

Workup

  1. temperaturewarmed on a steam bath for 15 minutes
  2. temperatureCooling
  3. filtrationfiltration

Sources & evidence

ORD record
ord-97374267c2cf42dc820f34b832cad73a
Source dataset
uspto-grants-1987_09
Patent number
US04691016

Reaction notes

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