反应详情

Approximately 151 g of 1,2-dodecanediol and ~150 g of toluene were charged to a 1 liter reactor equipped with agitator, heater and Dean-Stark tube with condenser and provision for using a nitrogen vapor space blanket. The contents were heated up to ~75° C., and 45 g of boric acid was added. The mixture was heated up to 155° C. over a period of ~5 hours until water evolution stopped. The solvent was removed by vacuum distillation and the product was filtered hot through diatomaceous earth. The product was a viscous, clear yellow fluid.

1. customequipped with agitator, heater and Dean-Stark tube with condenser
2. temperatureThe contents were heated up to ~75° C.
3. customThe solvent was removed by vacuum distillation
4. filtrationthe product was filtered hot through diatomaceous earth