HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzylpiperazine → 6[4-(Phenylmethyl)-1-piperazinyl]-5,8-quinoxalinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzylpiperazine | HCID 75994 | — |
| Reactant | 5,8-Quinoxalinedione | HCID 11355645 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 6[4-(Phenylmethyl)-1-piperazinyl]-5,8-quinoxalinedione | HCID 13957258 | 32.9% |
Reaction Steps
A mixture of 160 mg of 5,8-quinoxalinedione and 352 mg of 1-benzylpiperazine in 10 ml of dioxane was stirred or 3 hours. The solvent was then removed and the residue triturated with ether. This solid was collected, washed with ether and dried, giving 110 mg of the desired product, mp 165°-168° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04692449 |
| Source dataset | uspto-grants-1987_09 |
| ORD ID | ord-0f9728857e444b06ba4f3fd523a08075 |
| Source note | uspto-grants-1987_09 |