Acetic Anhydride → 2-Methyl[1,3]oxazolo[4,5-c]pyridine

HRID 2308957Notes

Reaction equation

HRID 2308957 reaction equation

[NH2:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[OH:8].[C:9](OC(=O)C)(=O)[CH3:10]>>[CH3:9][C:10]1[O:8][C:7]2[CH:6]=[CH:5][N:4]=[CH:3][C:2]=2[N:1]=1

Participants

3

Reactant 2

HCID 7918Acetic Anhydride

HCID 2333923-Amino-4-hydroxypyridine

Product 1

HCID 146662242-Methyl[1,3]oxazolo[4,5-c]pyridine

Procedure

3-Amino-4-hydroxypyridine was reacted with acetic anhydride to afford 4.7 g of 2-methyloxazolo[4,5-c]pyridine; mp 56°-58° C.

Sources & evidence

ORD record: ord-de5d9fb97619417890067dc8c1a82a8f
Source dataset: uspto-grants-1987_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04692443

Reaction notes

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