HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Glyoxylic Acid → Trans 4-(2,5-dimethyl-3-furyl)-4-oxo-2-butenoic Acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Glyoxylic Acid | HCID 760 | — |
| Edukt | 3-Acetyl-2,5-dimethylfuran | HCID 61527 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | Trans 4-(2,5-dimethyl-3-furyl)-4-oxo-2-butenoic Acid | HCID 13565867 | 14,2% |
Reaktionsschritte
As in Example 1, one starts out with 9 g of 3-acetyl 2.5-dimethylfuran (J. Am. Chem. Soc., 70 739 (1948)), 6 g glyoxylic acid and 6 cm3 water. Following chromatography on silica (eluent: petroleum ether-ethyl acetate (2-8), recrystallization in ethyl acetate, 1.8 g of the expected product is obtained. MP=144°-147° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04694019 |
| Quelldatensatz | uspto-grants-1987_09 |
| ORD ID | ord-7053e5b61ed6406cbd5d0791d2f73b7d |
| Quellennotiz | uspto-grants-1987_09 |