Benzoyl chloride → HCID 13958849, compound

HRID 2309272Notes

Reaction equation

[C:1](Cl)(=[O:8])[C:2]1C=CC=C[CH:3]=1.[OH:10][C:11]1[C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=2[S:14](=[O:22])(=[O:21])[N:13]([CH3:23])[C:12]=1[C:24]1[O:28][C:27]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[N:26][N:25]=1>>[CH3:23][N:13]1[C:12]([C:24]2[O:28][C:27]([C:29]3[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=3)=[N:26][N:25]=2)=[C:11]([O:10][C:1](=[O:8])[CH2:2][CH3:3])[C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=2[S:14]1(=[O:21])=[O:22]

Participants

Reactant 2

HCID 7412Benzoyl chloride

HCID 135838388HCID 135838388, compound

Product 1

HCID 13958849HCID 13958849, compound

Procedure

Following the procedures of Example 5, but substituting propionyl chloride for benzoyl chloride, 4-hydroxy-2-methyl-3-(2-phenyl-1,3,4-oxadiazol-5-yl)-1,2-benzothiazine 1,1-dioxide was acylated to give the title product.

Sources & evidence

ORD record: ord-71f7601064e744f1a2424fbf0621ba85
Source dataset: uspto-grants-1987_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04694080

Reaction notes

Loading…