HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 3503190, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | (1,1-Dioxido-3-oxo-1,2-benzothiazol-2(3h)-yl)acetonitrile | HCID 239728 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Product | HCID 3503190 | HCID 3503190 | — |
Reaction Steps
To a suspension of N-cyanomethylsaccharin (276 g) in methanol (1000 ml) was added dropwise 28% sodium methoxide (145 ml) over 30 minutes at 5°-10° C. After stirring at 5°-10° C. for 1 hour, 6N HCl (ca. 230 ml) was added dropwise maintaining the temperature at 10°-15° C. The resulting crystals were collected by filtration, washed with water and dried in vacuo at 50° C. for 16 hours to give o-carbomethoxy-N-cyanomethylbenzenesulfonamide, 264 g (78.7%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04694080 |
| Source dataset | uspto-grants-1987_09 |
| ORD ID | ord-d1ef37a953b040b8bad33f1e5f0d71f6 |
| Source note | uspto-grants-1987_09 |