反应详情

A solution of the product from Preparation 2 (5.0 g) in water (20 ml) was treated with 2N sodium carbonate (6.55 ml) and warmed at 35° for 45 mins. The resulting slurry was cooled to 0° and the solid was filtered off, washed with water and dried to give the title compound (2.8 g) m.p. 127°-129°.

1. temperaturewarmed at 35° for 45 mins
2. temperatureThe resulting slurry was cooled to 0°
3. filtrationthe solid was filtered off
4. washwashed with water
5. customdried