Phosphoric Acid → HCID 70083133, compound

HRID 2309423Notes

Reaction equation

HRID 2309423 reaction equation
[CH3:1][N:2]1[C:14]2[CH2:13][CH2:12][CH:11]([CH2:15][N:16]3[CH:20]=[CH:19][N:18]=[C:17]3[CH3:21])[C:10](=[O:22])[C:9]=2[C:8]2[C:3]1=[CH:4][CH:5]=[CH:6][CH:7]=2.[P:23](=[O:27])([OH:26])([OH:25])[OH:24]>O>[P:23]([OH:27])([OH:26])([OH:25])=[O:24].[CH3:1][N:2]1[C:14]2[CH2:13][CH2:12][CH:11]([CH2:15][N:16]3[CH:20]=[CH:19][N:18]=[C:17]3[CH3:21])[C:10](=[O:22])[C:9]=2[C:8]2[C:3]1=[CH:4][CH:5]=[CH:6][CH:7]=2

Participants

4

Reactant 2

HCID 1004Phosphoric AcidHCID 4595Ondansetron

Product 1

HCID 70083133HCID 70083133, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one (0.61 g) was dissolved in a hot mixture of phosphoric acid (90%, 0.13 ml) and water (10 ml), filtered through Hyflo and allowed to crystallize to give the title compound (0.5 g) m.p. 225°

Workup

  1. filtrationfiltered through Hyflo
  2. customto crystallize

Sources & evidence

ORD record
ord-0bb75869f9f64259845f15acb1b71095
Source dataset
uspto-grants-1987_09
Patent number
US04695578

Reaction notes

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