But-2-enal → HCID 54569326, compound

Participants

Reaction Steps

The aldehyde, 2-methyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-enal, which had been prepared by using the procedure outlined in U.S. Pat. No. 4,052,341 Example IV-1, was reacted essentially following the procedure described in Example I for isomerizing the α,β double bond to the β,γ position. In this case the butenal (19.2 g, 0.1 mole) was reacted with potassium t-butoxide (16.8 g, 0.15 mole) in 1,2-dimethoxyethane (DME, 200 ml) at 15°-20° C. by feeding in the butenal over 30 minutes, stirring for an additional 15 minutes and then rapidly quenching with aqueous 20% acetic acid (75 ml).

Provenance & Evidence