o-(Trifluoromethyl)benzaldehyde → Pyridine, 2-methyl-6-[2-(trifluoromethyl)phenyl]-

HRID 2309738Notes

Reaction equation

HRID 2309738 reaction equation
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:13]=[C:12]([CH3:14])[CH:11]=[CH:10][CH:9]=1.[F:15][C:16]([F:26])([F:25])C1C=CC=CC=1C=O>>[F:15][C:16]([F:26])([F:25])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:13]=[C:12]([CH3:14])[CH:11]=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 123067o-(Trifluoromethyl)benzaldehydeHCID 12380163HCID 12380163, compound

Product 1

HCID 21275753Pyridine, 2-methyl-6-[2-(trifluoromethyl)phenyl]-

Procedure

6-(2-trifluoromethylphenyl)-2-methylpyridine was prepared substantially according to the procedures of Example 1 for prearing 6-(2-chlorophenyl)-2-methylpyridine except 2-trifluoromethylbenzaldehyde was used to afford 6-(2-trifluoromethylphenyl)-2-methylpyridine.

Workup

  1. custom6-(2-trifluoromethylphenyl)-2-methylpyridine was prepared substantially

Sources & evidence

ORD record
ord-03bd82f2f90a480aa393eab757c7bf08
Source dataset
uspto-grants-1987_09
Patent number
US04696938

Reaction notes

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