反应详情

A mixture of 8.98 g of 2,2-dimethyl-4-[[4-(phenylmethoxy)phenoxy]methyl]-1,3-dioxolane, 15 g of a strongly acidic ion exchange resin and 200 ml of water was refluxed for 24 hours, then allowed to cool and methylene chloride was added. The mixture was filtered and the organic layer separated and saved. The aqueous layer was extracted several times with methylene chloride. All organic solutions were combined, dried and evaporated, giving 3.0 g of the desired compound, mp 125°-127° C.

1. temperaturewas refluxed for 24 hours
2. temperatureto cool
3. filtrationThe mixture was filtered
4. customthe organic layer separated
5. extractionThe aqueous layer was extracted several times with methylene chloride
6. customdried
7. customevaporated