4,5-Diaminopyrimidine → N-[3-Methoxy-4-(7H-purin-8-yl)phenyl]methanesulfonamide

HRID 2309876Notes

Reaction equation

HRID 2309876 reaction equation
[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][N:5]=[CH:4][N:3]=1.[CH3:9][O:10][C:11]1[CH:19]=[C:18]([NH:20][S:21]([CH3:24])(=[O:23])=[O:22])[CH:17]=[CH:16][C:12]=1[C:13](O)=O>>[CH3:9][O:10][C:11]1[CH:19]=[C:18]([NH:20][S:21]([CH3:24])(=[O:23])=[O:22])[CH:17]=[CH:16][C:12]=1[C:13]1[NH:8][C:7]2[C:2](=[N:3][CH:4]=[N:5][CH:6]=2)[N:1]=1

Participants

3

Reactant 2

HCID 837034,5-DiaminopyrimidineHCID 121193062-Methoxy-4-[(methylsulfonyl)amino]benzoic acid

Product 1

HCID 13284519N-[3-Methoxy-4-(7H-purin-8-yl)phenyl]methanesulfonamide

Procedure

Prepared analogously to Example 14 from 4,5-diaminopyrimidine and 2-methoxy-4-methanesulfonylamino-benzoic acid.

Sources & evidence

ORD record
ord-3958e3bdbae643dd8ad4aa129591fd78
Source dataset
uspto-grants-1987_09
Patent number
US04696931

Reaction notes

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