Methanesulfonyl chloride → HCID 13284513, compound

HRID 2309891Notes

Reaction equation

HRID 2309891 reaction equation
Cl.Cl.[CH3:3][N:4]([CH3:21])[C:5]1[CH:10]=[C:9]([OH:11])[CH:8]=[CH:7][C:6]=1[C:12]1[NH:13][C:14]2[C:15]([N:20]=1)=[N:16][CH:17]=[CH:18][CH:19]=2.[CH3:22][S:23](Cl)(=[O:25])=[O:24]>>[CH3:3][N:4]([CH3:21])[C:5]1[CH:10]=[C:9]([O:11][S:23]([CH3:22])(=[O:25])=[O:24])[CH:8]=[CH:7][C:6]=1[C:12]1[NH:13][C:14]2[C:15]([N:20]=1)=[N:16][CH:17]=[CH:18][CH:19]=2

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 136332139HCID 136332139, compound

Product 1

HCID 13284513HCID 13284513, compound

Procedure

Prepared analogously to Example 56 from 2-(2'-dimethylamino-4'-hydroxy-phenyl)-imidazo[4,5-b]pyridine dihydrochloride and methanesulfonyl chloride. The product was purified over silica gel column [eluant:first methylene chloride, then methylene chloride/ethanol (50:1)].

Workup

  1. customThe product was purified over silica gel column [eluant

Sources & evidence

ORD record
ord-622c250eb73244508a81bf667ce8e790
Source dataset
uspto-grants-1987_09
Patent number
US04696931

Reaction notes

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