Methyl 4,5-dibromo-3-fluorothiophene-2-carboxylate → Methyl 4-bromo-5-(3-cyano-4-isobutoxyphenyl)-3-fluorothiophene-2-carboxylate
Reaction equation
[Br:17][c:18]1[c:19]([F:28])[c:20]([C:24](=[O:25])[O:26][CH3:27])[s:21][c:22]1[Br:23].[C:1](#[N:2])[c:3]1[cH:4][c:5]([B:14]([OH:15])[OH:16])[cH:6][cH:7][c:8]1[O:9][CH2:10][CH:11]([CH3:12])[CH3:13]>>[C:1](#[N:2])[c:3]1[cH:4][c:5](-[c:22]2[c:18]([Br:17])[c:19]([F:28])[c:20]([C:24](=[O:25])[O:26][CH3:27])[s:21]2)[cH:6][cH:7][c:8]1[O:9][CH2:10][CH:11]([CH3:12])[CH3:13]Participants
3
Sources & evidence
- ORD record
- ord-11285e60fff14070acbc468b58be35cd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…