4-Fluorophenylacetyl chloride → 3-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}propyl (4-fluorophenyl)acetate
Reaction equation
[F:23][c:24]1[cH:25][cH:26][c:27]([CH2:30][C:31](=[O:32])[Cl:33])[cH:28][cH:29]1.[OH:1][CH2:2][CH2:3][CH2:4][N:5]1[CH2:6][CH2:7][CH:8]([c:11]2[cH:12][c:13]([NH:17][C:18]([CH:19]([CH3:20])[CH3:21])=[O:22])[cH:14][cH:15][cH:16]2)[CH2:9][CH2:10]1>>[O:1]([CH2:2][CH2:3][CH2:4][N:5]1[CH2:6][CH2:7][CH:8]([c:11]2[cH:12][c:13]([NH:17][C:18]([CH:19]([CH3:20])[CH3:21])=[O:22])[cH:14][cH:15][cH:16]2)[CH2:9][CH2:10]1)[C:31]([CH2:30][c:27]1[cH:26][cH:25][c:24]([F:23])[cH:29][cH:28]1)=[O:32]Participants
3
Sources & evidence
- ORD record
- ord-d2c1fd36ed604df7bba2e5f1c9ffe544
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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