Methyl chloroformate → 1-(Methoxycarbonyl)piperidin-4-yl 7-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3,4-dihydroisoquinoline-2(1h)-carboxylate
Reaction equation
[Cl:1][C:2](=[O:3])[O:4][CH3:5].[NH2:6][c:7]1[n:8][c:9]([N:32]2[CH2:33][CH2:34][N:35]([CH3:38])[CH2:36][CH2:37]2)[cH:10][c:11](-[c:13]2[cH:14][cH:15][c:16]3[c:21]([cH:22]2)[CH2:20][N:19]([C:23](=[O:24])[O:25][CH:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[CH2:18][CH2:17]3)[n:12]1>>[C:2](=[O:3])([O:4][CH3:5])[N:29]1[CH2:28][CH2:27][CH:26]([O:25][C:23]([N:19]2[CH2:18][CH2:17][c:16]3[cH:15][cH:14][c:13](-[c:11]4[cH:10][c:9]([N:32]5[CH2:33][CH2:34][N:35]([CH3:38])[CH2:36][CH2:37]5)[n:8][c:7]([NH2:6])[n:12]4)[cH:22][c:21]3[CH2:20]2)=[O:24])[CH2:31][CH2:30]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-651f95dcc17b4be1bebf4672c9c7d2f5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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