HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzoic Acid → 4-(1-Methylheptyloxycarbonyl)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzoic Acid | HCID 135 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | (R)-2-Octanol | HCID 80080 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 4-(1-Methylheptyloxycarbonyl)phenol | HCID 11010379 | 43% |
Reaction Steps
27.6 g of p-hydroxybenzoic acid and 39.0 g of (R)-2-octanol were refluxed for 10 hours in 300 ml of benzene in the presence of 0.5 ml of conc. sulfuric acid. Then, the reaction solution was cooled to the room temperature, and then concentrated and purified by column chromatography, to obtain 21.5 g of p-hydroxybenzoic acid 1-methylheptyl ester. (yield: 43%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04844835 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-9a63337d10b54f90af339903302db2f4 |
| Source note | uspto-grants-1989_07 |