2-Chloro-5-(trifluoromethyl)phenylboronic acid → 4-amino-8-[2-chloro-5-(trifluoromethyl)phenyl]-N-propyl-cinnoline-3-carboxamide

HRID 2310254Notes

Reaction equation

HRID 2310254 reaction equation
[Cl:19][c:20]1[c:21]([B:30]([OH:31])[OH:32])[cH:22][c:23]([C:26]([F:27])([F:28])[F:29])[cH:24][cH:25]1.[NH2:1][c:2]1[c:3]([C:13](=[O:14])[NH:15][CH2:16][CH2:17][CH3:18])[n:4][n:5][c:6]2[c:7]([Br:12])[cH:8][cH:9][cH:10][c:11]12>>[NH2:1][c:2]1[c:3]([C:13](=[O:14])[NH:15][CH2:16][CH2:17][CH3:18])[n:4][n:5][c:6]2[c:7](-[c:21]3[c:20]([Cl:19])[cH:25][cH:24][c:23]([C:26]([F:27])([F:28])[F:29])[cH:22]3)[cH:8][cH:9][cH:10][c:11]12

Participants

3

Reactant 2

HCID 27826702-Chloro-5-(trifluoromethyl)phenylboronic acidHCID 140123264-Amino-8-bromo-N-propylcinnoline-3-carboxamide

Product 1

HCID 251320684-amino-8-[2-chloro-5-(trifluoromethyl)phenyl]-N-propyl-cinnoline-3-carboxamide

Sources & evidence

ORD record
ord-5cdbd2e713994811a96e562dfea64e84
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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