2-(Bis(methylsulfanyl)methylidene)propanedinitrile → 5-Amino-4-cyano-3-methylthio-1-(3-trifluoromethylbenzyl)-pyrazole

Participants

Reaction Conditions

Reaction Steps

8.5 g of 1,1-dicyano-2,2-bis-(methylmercapto)-ethylene and 9.5 g of 3-trifluoromethyl-benzylhydrazine are mixed in 100 ml of ethanol. The mixture is stirred for 15 hours at 20° C. and the solvent is evaporated in a rotary evaporator. The residue is triturated in petroleum ether. 12.4 g (80% of theory) of 1-(3-trifluoromethylbenzyl)-3-methylmercapto-4-cyano-5-amino-pyrazol of melting point 142° C. are obtained.

Provenance & Evidence