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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 23106Generated: October 25, 2026

3-Thiophenacetic acid → N-[(3thienyl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/23106

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Thiophenacetic acidHCID 23404—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3thienyl)acetyl]alanine Iso-butyl EsterHCID 53969374—

Reaction Steps

Following General Procedure BI above, and using 3-thiopheneacetic acid (Aldrich) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06849650B2
Source datasetuspto-grants-2005_02
ORD IDord-a06cd8cc56df4f4f8e933358ded82537
Source noteuspto-grants-2005_02