Acetic Acid → 1-(4-Fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]-decan-4-one
Reaction equation
[C:32]([OH:33])(=[O:34])[CH3:35].[CH3:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][cH:8][cH:9][c:10]([CH:12]=[O:13])[c:11]12.[CH3:41][CH2:42][O:43][CH2:44][CH3:45].[Cl:38][CH2:39][Cl:40].[F:14][c:15]1[cH:16][cH:17][c:18]([N:21]2[CH2:22][NH:23][C:24](=[O:31])[C:25]23[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]3)[cH:19][cH:20]1.[Na+:37].[OH-:36]>>[CH3:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][cH:8][cH:9][c:10]([CH2:12][N:28]3[CH2:27][CH2:26][C:25]4([N:21]([c:18]5[cH:17][cH:16][c:15]([F:14])[cH:20][cH:19]5)[CH2:22][NH:23][C:24]4=[O:31])[CH2:30][CH2:29]3)[c:11]12Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-4414f71c8551479ab7e8b056ebf47956
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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