2-(1-(4-fluorobenzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methylthiazole-5-carboxamide → 2-(3-(4-Fluorobenzyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carbonitrile

HRID 2310700Notes

Reaction equation

HRID 2310700 reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][n:7]2[c:8](=[O:9])[n:10](-[c:11]3[s:12][c:13]([C:14]([NH2:15])=[O:16])[c:17]([CH3:18])[n:19]3)[cH:20][n:21]2)[cH:22][cH:23]1.[F:24][c:25]1[cH:26][cH:27][c:28]([CH2:29][N:30]2[C:31](=[O:44])[N:32]([c:35]3[s:36][c:37]([C:41](=[O:42])[NH2:43])[c:38]([CH3:40])[n:39]3)[CH2:33][CH2:34]2)[cH:45][cH:46]1>>[F:24][c:25]1[cH:26][cH:27][c:28]([CH2:29][N:30]2[C:31](=[O:44])[N:32]([c:35]3[s:36][c:37]([C:41]#[N:43])[c:38]([CH3:40])[n:39]3)[CH2:33][CH2:34]2)[cH:45][cH:46]1

Participants

3

Reactant 2

HCID 441936012-(1-(4-fluorobenzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methylthiazole-5-carboxamideHCID 580314432-(3-(4-Fluorobenzyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxamide

Product 1

HCID 579197612-(3-(4-Fluorobenzyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carbonitrile

Sources & evidence

ORD record
ord-d548fda185a64855ba1aa2c1bd7e690d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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