Pyrimidine, 5-bromo-2-methoxy- → 3-Cyclobutyl-7-{[2-(methyloxy)-5-pyrimidinyl]oxy)-2,3,4,5-tetrahydro-1H-3-benzazepine

HRID 2310751Notes

Reaction equation

HRID 2310751 reaction equation
[Br:17][c:18]1[cH:19][n:20][c:21]([O:24][CH3:25])[n:22][cH:23]1.[CH:1]1([N:5]2[CH2:6][CH2:7][c:8]3[c:9]([cH:12][c:13]([OH:16])[cH:14][cH:15]3)[CH2:10][CH2:11]2)[CH2:2][CH2:3][CH2:4]1>>[CH:1]1([N:5]2[CH2:6][CH2:7][c:8]3[c:9]([cH:12][c:13]([O:16][c:18]4[cH:19][n:20][c:21]([O:24][CH3:25])[n:22][cH:23]4)[cH:14][cH:15]3)[CH2:10][CH2:11]2)[CH2:2][CH2:3][CH2:4]1

Participants

3

Reactant 2

HCID 139657Pyrimidine, 5-bromo-2-methoxy-HCID 100820813-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[D]azepin-7-OL

Product 1

HCID 100649013-Cyclobutyl-7-{[2-(methyloxy)-5-pyrimidinyl]oxy)-2,3,4,5-tetrahydro-1H-3-benzazepine

Sources & evidence

ORD record
ord-206a946067e140c78f7444cf65be7e46
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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