Acetone → 4-[3-Chloro-2-(1-cyclohexyl-2-oxo-pyrrolidin-3-ylmethyl)-benzo[b]thiophen-6-yloxymethyl]-benzoic acid methyl ester
Reaction equation
[C:27](=[O:28])([O-:29])[O-:30].[CH3:33][O:34][C:35]([c:36]1[cH:37][cH:38][c:39]([CH2:42][Br:43])[cH:40][cH:41]1)=[O:44].[CH3:45][C:46](=[O:47])[CH3:48].[Cl:1][c:2]1[c:3]2[c:4]([s:5][c:6]1[CH2:7][CH:8]1[C:9](=[O:19])[N:10]([CH:13]3[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]3)[CH2:11][CH2:12]1)[cH:20][c:21]([OH:24])[cH:22][cH:23]2.[Cs+:31].[Cs+:32].[I-:25].[Na+:26]>>[Cl:1][c:2]1[c:3]2[c:4]([s:5][c:6]1[CH2:7][CH:8]1[C:9](=[O:19])[N:10]([CH:13]3[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]3)[CH2:11][CH2:12]1)[cH:20][c:21]([O:24][CH2:42][c:39]1[cH:38][cH:37][c:36]([C:35]([O:34][CH3:33])=[O:44])[cH:41][cH:40]1)[cH:22][cH:23]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-322237e5b23b4453af444573223dbf3c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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