3-Bromophenol → 8-hydroxy-8-(7-hydroxy-2,3-dihydro-1,4-benzodioxin-6-yl)-6-(4-methoxybenzyl)-6,8-dihydro-7H-[1,3]thiazolo[5,4-e]indol-7-one
Reaction equation
[Br:12][c:13]1[cH:14][c:15]([OH:16])[cH:17][cH:18][cH:19]1.[CH3:20][O:21][c:22]1[cH:23][cH:24][c:25]([CH2:26][N:27]2[C:28](=[O:40])[C:29](=[O:39])[c:30]3[c:31]4[c:32]([cH:33][cH:34][c:35]32)[n:36][cH:37][s:38]4)[cH:41][cH:42]1.[F:43][C:44]([F:45])([F:46])[c:47]1[o:48][c:49]([CH2:50][N:51]2[c:52]3[c:53]([cH:54][cH:55][cH:56][cH:57]3)[C:58](=[O:59])[C:60]2=[O:61])[cH:62][cH:63]1.[O:1]1[c:2]2[c:3]([cH:7][c:8]([OH:11])[cH:9][cH:10]2)[O:4][CH2:5][CH2:6]1>>[O:1]1[c:2]2[c:3]([cH:7][c:8]([OH:11])[c:9]([C:29]3([OH:39])[C:28](=[O:40])[N:27]([CH2:26][c:25]4[cH:24][cH:23][c:22]([O:21][CH3:20])[cH:42][cH:41]4)[c:35]4[c:30]3[c:31]3[c:32]([cH:33][cH:34]4)[n:36][cH:37][s:38]3)[cH:10]2)[O:4][CH2:5][CH2:6]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-8c38df6a44b348d8b7502947c1b71a29
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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