Methanesulfonyl chloride → 2-(2-{[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-methanesulfonyl-amino}-ethyl)-piperidine-1-carboxylic acid tert-butyl ester

HRID 2310979Notes

Reaction equation

HRID 2310979 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:14][CH2:15][NH:16][CH2:17][c:18]2[cH:19][c:20](-[c:24]3[n:25][c:26]([Cl:30])[n:27][cH:28][cH:29]3)[cH:21][cH:22][cH:23]2)[CH2:10][CH2:11][CH2:12][CH2:13]1.[CH3:31][S:32]([Cl:33])(=[O:34])=[O:35]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:14][CH2:15][N:16]([CH2:17][c:18]2[cH:19][c:20](-[c:24]3[n:25][c:26]([Cl:30])[n:27][cH:28][cH:29]3)[cH:21][cH:22][cH:23]2)[S:32]([CH3:31])(=[O:34])=[O:35])[CH2:10][CH2:11][CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 866032762-{2-[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 866032772-(2-{[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-methanesulfonyl-amino}-ethyl)-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-becb3a347a1f4db9bb892c560626e205
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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